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Convergence of evidence from a methylome-wide CpG-SNP association study and GWAS of major depressive disorder.
Aberg KA, Shabalin AA, Chan RF, Zhao M, Kumar G, van Grootheest G, Clark SL, Xie LY, Milaneschi Y, Penninx BWJH, van den Oord EJCG. Aberg KA, et al. Transl Psychiatry. 2018 Aug 22;8(1):162. doi: 10.1038/s41398-018-0205-8. Transl Psychiatry. 2018. PMID: 30135428 Free PMC article.
Of particular interest are methylation sites (CpGs) that are created or destroyed by the alleles of single-nucleotide polymorphisms (SNPs), as these so-called CpG-SNPs may show variation in methylation levels on top of what can be explained by the sequence variation. Using sequen …
Of particular interest are methylation sites (CpGs) that are created or destroyed by the alleles of single-nucleotide polymorphisms (SNPs), …
Host genetics influences the relationship between the gut microbiome and psychiatric disorders.
Martins-Silva T, Salatino-Oliveira A, Genro JP, Meyer FDT, Li Y, Rohde LA, Hutz MH, Tovo-Rodrigues L. Martins-Silva T, et al. Prog Neuropsychopharmacol Biol Psychiatry. 2021 Mar 2;106:110153. doi: 10.1016/j.pnpbp.2020.110153. Epub 2020 Oct 30. Prog Neuropsychopharmacol Biol Psychiatry. 2021. PMID: 33130294
In this study, we aimed to evaluate the role of genetic variants associated with the gut microbiome in the susceptibility of individuals to four psychiatric disorders: schizophrenia (SCZ), attention-deficit/hyperactivity disorder (ADHD), autism spectrum disorder (AS …
In this study, we aimed to evaluate the role of genetic variants associated with the gut microbiome in the susceptibility of individuals to …
Evidence for association of an ACCN1 gene variant with response to lithium treatment in Sardinian patients with bipolar disorder.
Squassina A, Manchia M, Borg J, Congiu D, Costa M, Georgitsi M, Chillotti C, Ardau R, Mitropoulos K, Severino G, Del Zompo M, Patrinos GP. Squassina A, et al. Pharmacogenomics. 2011 Nov;12(11):1559-69. doi: 10.2217/pgs.11.102. Epub 2011 Oct 3. Pharmacogenomics. 2011. PMID: 21961650
AIMS: Bipolar disorder (BD) is a lifelong psychiatric illness characterized by manic and depressive episodes affecting 1-5% of the general population. ...
AIMS: Bipolar disorder (BD) is a lifelong psychiatric illness characterized by manic and depressive episodes affecting 1-5% of …